Welcome to the lab!
We are interested in the ecological and evolutionary factors shaping bacteriophage genomes.
We use laboratory work and bioinformatics to understand how these parts influence the virus itself, their bacterial hosts, and the microbiomes they exist in.
We work by analyzing genomes in silico, synthesizing them in vitro, and generally dissecting and reassembling phages - specifically single-stranded DNA phages of the family Microviridae.
Currently, we are mostly focused on studying their interaction with bacterial hosts and competition with other phages, as well as exploring microvirus diversity in humans and elsewhere.
In the future, we hope to leverage knowledge gained from this research into building customized phages for phage therapy and ecosystem engineering.
News
News
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New labspace, new virus structures The lab has successfully made our move into LSE006, our new space for years to come.
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More funding from the NIH! More good news! The National Insitute of Health are funding our R03 grant "Mechanisms and dynamics of superinfection exclusion in microviral prophage populations".
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Alex presents at ASM2024 Atlanta Paul and Alex travel to the 2024 meeting of the American Society of Microbiology in Atlanta, Georgia
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New phage, new preprint Wherein Paul describes a new phage infecting Rhodobacter with Friend of the Lab and Cryo-EM Wizard Pavol Bardy.
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Hiring Postdoc! We are hiring a postdoctoral reserearcher to isolate and characterize microviruses of the human gut. Learn more here:...